Anti-TTF2 FOXE1 Antibody
Boster Bio Anti-TTF2 FOXE1 Antibody (Catalog # A02831-1) . Tested in IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
Probable transcription factor. Could be involved in thyroid gland organogenesis.<br><br>Buanne P., Genomics 51:233-242(1998).<br>Hillier L.W., Nature 424:157-164(2003).<br>The MGC Project Team; Genome Res. 14:2121-2127(2004).
Synonyms
Forkhead box protein E1; Forkhead box protein E2; Forkhead-related protein FKHL15; HFKH4; HNF-3/fork head-like protein 5; HFKL5; Thyroid transcription factor 2; TTF-2; FOXE1; FKHL15, FOXE2, TITF2, TTF2
Gene Name
FOXE1
UniProt
O00358
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from internal of human TTF2.
Clonality
Polyclonal
Tissue Specificity
Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.
Applications
IF
Field of Research
Domain Families, Epigenetics and Nuclear Signaling, Forkhead Box, Transcription, Transcription Factors
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Immunofluorescence: 1:100~1:500
Form
Liquid
Function
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. .
Molecular Weight
38076 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Forkhead box protein E1
Subcellular Location
Nucleus .
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