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Anti-Keratin 20 KRT20 Antibody

Boster Bio Anti-Keratin 20 KRT20 Antibody (Catalog # A02828-1) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine By similarity.<br><br>Qin Zhou, Mol. Biol. Cell, Jul 2003; 14: 2959.<br>Qin Zhou, J. Biol. Chem., Jun 2006; 281: 16453 - 16461.<br>F Smedts, Am. J. Pathol., Feb 1993; 142: 403.<br>RK Miller, J. Cell Biol., May 1991; 113: 843.

Synonyms

Keratin, type I cytoskeletal 20; Cytokeratin-20; CK-20; Keratin-20; K20; Protein IT; KRT20

Gene Name

KRT20

UniProt

P35900

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Keratin 20.

Clonality

Polyclonal

Tissue Specificity

Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa. .

Applications

WB, IHC

Field of Research

Cancer, Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Signal Transduction, Tumor Biomarkers

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) . .

Molecular Weight

48487 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Keratin, type I cytoskeletal 20

Subcellular Location

Cytoplasm .

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