Anti-TRADD Antibody
Boster Bio Anti-TRADD Antibody catalog # A02785-1. Tested in WB applications. This antibody reacts with Human, Monkey, Mouse.
Product Specifications
Synonyms
Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain; TRADD
Gene Name
TRADD
UniProt
Q15628
Host
Rabbit
Reactivity
Human, Mouse, Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300
Tissue Specificity
Found in all examined tissues.
Applications
WB
Purification
Immunogen affinity purified
Dilution
WB, 1:500-1:2000
Form
Liquid
Function
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity) . Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. .
Molecular Weight
34247 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Subcellular Location
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Shuttles between the cytoplasm and the nucleus. .
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