Anti-CAF-1 p150 CHAF1A Antibody
Boster Bio Anti-CAF-1 p150 CHAF1A Antibody catalog # A02732-1. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Chromatin assembly factor 1 subunit A; CAF-1 subunit A; Chromatin assembly factor I p150 subunit; CAF-I 150 kDa subunit; CAF-I p150; hp150; CHAF1A; CAF, CAF1P150
Gene Name
CHAF1A
UniProt
Q13111
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from CAF-1 p150 . at AA range: 300-380
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity) . .
Molecular Weight
106926 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Chromatin assembly factor 1 subunit A
Subcellular Location
Nucleus . DNA replication foci.
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