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HCAIX-IN-5

HCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].

Product Specifications

CAS Number

2451479-57-3

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hcaix-in-5.html

Purity

98.32

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC2=C(OC(C=C2)=O)C=C1)/C=C/C3=CC=C(C=C3)F

Molecular Formula

C18H12FNO3

Molecular Weight

309.29

References & Citations

[1]Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28 (15) :115586.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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