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Anti-14-3-3 beta YWHAB Antibody

Boster Bio Anti-14-3-3 beta YWHAB Antibody catalog # A02431. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

14-3-3 protein beta/alpha; Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1;14-3-3 protein beta/alpha, N-terminally processed; YWHAB

Gene Name

YWHAB

UniProt

P31946

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human 14-3-3 beta. AA range:41-90

Applications

WB

Purification

Immunogen affinity purified

Dilution

WB, 1:500-1:2000

Form

Liquid

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13. .

Molecular Weight

28082 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02431

Product MSDS

https://www.bosterbio.com/msds?sku=A02431

Fragment

IgG

Other Gene Names

14-3-3 protein beta/alpha

Subcellular Location

Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

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