Anti-GAB2 (Ab-159) Antibody
Boster Bio Anti-GAB2 (Ab-159) Antibody (Catalog # A02386-2) . Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Background
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.<br>
<br>
Nishida K., Blood 93:1809-1816(1999).<br>
Nagase T., DNA Res. 5:31-39(1998).<br>
Taylor T.D., Nature 440:497-500(2006).
Gene Name
GAB2
UniProt
Q9UQC2
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized non-phosphopeptide derived from human GAB2 around the phosphorylation site of serine 159 (K-S-S (p) -A-P) .
Clonality
Polyclonal
Applications
WB, IHC
Field of Research
Adapters, Alzheimer's Disease, Cancer, Cytoplasmic, Neurodegenerative Disease, Neurology Process, Neuroscience, Signal Transduction
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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