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Anti-GAB2 (Ab-159) Antibody

Boster Bio Anti-GAB2 (Ab-159) Antibody (Catalog # A02386-2) . Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Background

Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.<br> <br> Nishida K., Blood 93:1809-1816(1999).<br> Nagase T., DNA Res. 5:31-39(1998).<br> Taylor T.D., Nature 440:497-500(2006).

Gene Name

GAB2

UniProt

Q9UQC2

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized non-phosphopeptide derived from human GAB2 around the phosphorylation site of serine 159 (K-S-S (p) -A-P) .

Clonality

Polyclonal

Applications

WB, IHC

Field of Research

Adapters, Alzheimer's Disease, Cancer, Cytoplasmic, Neurodegenerative Disease, Neurology Process, Neuroscience, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

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