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Anti-KCNJ5/Kir3.4 Antibody

Boster Bio Anti-KCNJ5/Kir3.4 Antibody (Catalog# A02160) . Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

KCNJ5; GIRK4; G protein-activated inward rectifier potassium channel 4; GIRK-4; Cardiac inward rectifier; CIR; Heart KATP channel; Inward rectifier K (+) channel Kir3.4; IRK-4; KATP-1; Potassium channel; inwardly rectifying subfamily J membe

Gene Name

KCNJ5

UniProt

P48544

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human KCNJ5. Immunogen sequence location: 370 - 419

Clonality

Polyclonal

Tissue Specificity

Islets, exocrine pancreas and heart. Expressed in the adrenal cortex, particularly the zona glomerulosa.

Applications

WB, IF, ICC, ELISA

Field of Research

Cardiovascular, Metabolism, Neuroscience, Neurotransmission, Plasma Membrane, Potassium Channels, Receptors / Channels, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

Molecular Weight

47668 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

G protein-activated inward rectifier potassium channel 4

Subcellular Location

Membrane; Multi-pass membrane protein.

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