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Anti-CDH23/OtoCadherin 23 Antibody

Boster Bio Anti-CDH23/OtoCadherin 23 Antibody (Catalog# A02149-2) . Tested in IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Gene Name

CDH23

UniProt

Q9H251

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human CDH23. Immunogen sequence location: 61-110

Clonality

Polyclonal

Tissue Specificity

Particularly strong expression in the retina. Found also in the cochlea.

Applications

IF, ICC, ELISA

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Molecular Weight

369494 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02149-2

Product MSDS

https://www.bosterbio.com/msds?sku=A02149-2

Fragment

Rabbit IgG

Other Gene Names

Cadherin-23

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

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