Anti-CDH23/OtoCadherin 23 Antibody

Boster Bio Anti-CDH23/OtoCadherin 23 Antibody (Catalog# A02149-2) . Tested in IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Gene Name

CDH23

UniProt

Q9H251

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human CDH23. Immunogen sequence location: 61-110

Clonality

Polyclonal

Tissue Specificity

Particularly strong expression in the retina. Found also in the cochlea.

Applications

IF, ICC, ELISA

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.