Anti-Urocortin UCN Antibody

Boster Bio Anti-Urocortin UCN Antibody (Catalog# A01807-1) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

UCN; Urocortin

Gene Name

UCN

UniProt

P55089

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human Urocortin. Immunogen sequence location: 71-120

Clonality

Polyclonal

Tissue Specificity

Keratinocytes in epidermis and the outer and inner root sheaths of hair follicles, epithelium of sebaceous and sweat glands, erector pili muscle, cutaneous blood vessel walls, cutaneous nerves and dermal mononuclear cells (PubMed:10690896) . Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) (at protein level) . Expressed in pituitary and adrenal glands (PubMed:10690896) . Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) .AS74

Applications

IHC-P, IF (paraffin), ELISA

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563) . Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563) . Plays a role in the establishment of normal hearing thresholds (By similarity) . Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity) .