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Anti-Oct-1 POU2F1 Antibody

Boster Bio Anti-Oct-1 POU2F1 Antibody (Catalog # A01766-2) . Tested in WB, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. <br> <br> Prefontaine G.G., Walther R., Giffin W. J. Biol. Chem. 274:26713-26719(1999) <br> Mahajan S.S., Wilson A.C. Mol. Cell. Biol. 20:919-928(2000)

Gene Name

POU2F1

UniProt

P14859

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Peptide sequence around aa.270~274 (T-P-K-R-I) derived from Human Oct-1.

Clonality

Polyclonal

Applications

WB, IF

Field of Research

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Transcription

Purification

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/ml

Form

Liquid

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

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