Anti-Sox-17 Antibody
Boster Bio Anti-Sox-17 Antibody catalog # A01665-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Transcription factor SOX-17; SOX17
Gene Name
SOX17
UniProt
Q9H6I2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from Sox-17 . at AA range: 90-170
Clonality
Polyclonal
Tissue Specificity
Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum. .
Applications
ELISA, WB
Purification
The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
Form
Liquid
Function
Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity) . .
Molecular Weight
44117 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Transcription factor SOX-17
Subcellular Location
Nucleus .
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