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Anti-p15 INK CDKN2B Antibody

Boster Bio Anti-p15 INK CDKN2B Antibody (Catalog # A01500-1) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.<br><br>Nynke Y. Rots, Blood, Apr 1999; 93: 2721 - 2729. <br>Stefan Faderl, Clin. Cancer Res., Jul 1999; 5: 1855. <br>George Wu, Mol. Biol. Cell, Mar 2007; 18: 1018 - 1029. <br>A. Koenig, Vet. Pathol., Jul 2002; 39: 458.

Synonyms

Cyclin-dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4B; CDKN2B; MTS2

Gene Name

CDKN2B

UniProt

P42772

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human p15 INK antibody.

Clonality

Polyclonal

Tissue Specificity

Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines. .

Applications

WB, IHC, IF

Field of Research

Cancer, Cancer Susceptibility, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Cell Type Markers, Epigenetics and Nuclear Signaling, Nuclear, Oncoproteins/Suppressors, Signaling Pathways, Stem Cells, Tags & Cell Markers, TGF Beta, Transcription, Tumor Associated, Tumor Suppressors

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Molecular Weight

14722 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Cyclin-dependent kinase 4 inhibitor B

Subcellular Location

Cytoplasm . Also found in the nucleus.

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