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Anti-CPE/Carboxypeptidase E Antibody

Boster Bio Anti-CPE/Carboxypeptidase E Antibody catalog # A01407. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Carboxypeptidase E; CPE;3.4.17.10; Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase; CPE

Gene Name

CPE

UniProt

P16870

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human CPE. AA range:427-476

Tissue Specificity

Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas. .

Applications

WB, IHC

Purification

Immunogen affinity purified

Form

Liquid

Function

Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.

Molecular Weight

53151 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Carboxypeptidase E

Subcellular Location

Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein . Secreted . Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions. .

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