Anti-Protein DBF4 homolog A DBF4 Antibody

Boster Bio Anti-Protein DBF4 homolog A DBF4 Antibody (Catalog # A01348-1) . Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.<br><br>Kumagai H., Mol. Cell. Biol. 19:5083-5095(1999).<br>Jiang W., EMBO J. 18:5703-5713(1999).<br>Ota T., Nat. Genet. 36:40-45(2004).

Synonyms

Protein DBF4 homolog A; Activator of S phase kinase; Chiffon homolog A; DBF4-type zinc finger-containing protein 1; DBF4; ASK, DBF4A, ZDBF1

Gene Name

DBF4

UniProt

Q9UBU7

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from N-terminal of human DBF4.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in testis and thymus. Expressed also in most cancer cells lines. .

Applications

Field of Research

Cell Biology, Cell Cycle, DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling, Kinases/Phosphatases

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Molecular Weight

76858 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Protein DBF4 homolog A

Subcellular Location

Nucleus .

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