Anti-KCNH1 Antibody
Boster Bio Anti-KCNH1 Antibody catalog # A01036-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Potassium voltage-gated channel subfamily H member 1; Ether-a-go-go potassium channel 1; EAG channel 1; h-eag; hEAG1; Voltage-gated potassium channel subunit Kv10.1; KCNH1; EAG, EAG1
Gene Name
KCNH1
UniProt
O95259
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNH1. AA range:720-769
Tissue Specificity
Highly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells.
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel (PubMed:22732247) . Channel properties may be modulated by subunit assembly, but not by cyclic nucleotides (By similarity) . Mediates IK (NI) current in myoblasts (PubMed:9738473) . Involved in the regulation of cell proliferation and differentiation, in particular adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (PubMed:23881642) . .
Molecular Weight
111423 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Potassium voltage-gated channel subfamily H member 1
Subcellular Location
Cell membrane ; Multi- pass membrane protein . Nucleus inner membrane ; Multi-pass membrane protein . Early endosome membrane . Perinuclear KCNH1 is located to NPC-free islands.
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