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Anti-Collagen III COL3A1 Antibody

Boster Bio Anti-Collagen III COL3A1 Antibody (Catalog # A00788-1) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.<br> <br> Arja Lamberg, J. Biol. Chem., May 1996; 271: 11988.<br> GW Conrad, J. Cell Biol., Mar 1980; 84: 501.<br> DR Keene, J. Cell Biol., Nov 1987; 105: 2393.<br> HM Wang, J. Histochem. Cytochem., Nov 1980; 28: 1215.

Synonyms

Collagen alpha-1 (III) chain; COL3A1

Gene Name

COL3A1

UniProt

P02461

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human collagen III.

Clonality

Polyclonal

Applications

WB, IHC, IF

Field of Research

Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Mesenchymal Stem Cells, Signal Transduction, Stem Cells

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

Molecular Weight

138564 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Collagen alpha-1 (III) chain

Subcellular Location

Secreted, extracellular space, extracellular matrix .

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