Anti-TTN/Titin Antibody
Boster Bio Anti-TTN/Titin Antibody catalog # A00540. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Titin;2.7.11.1; Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14; TTN
Gene Name
TTN
UniProt
Q8WZ42
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide from human protein at AA range: 161-210
Clonality
Polyclonal
Tissue Specificity
Isoforms 3, 7 and 8 are expressed in cardiac muscle. Isoform 4 is expressed in vertebrate skeletal muscle. Isoform 6 is expressed in skeletal muscle (at protein level) . .
Applications
IHC
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Dilution
IHC-P 1:50-200
Form
Liquid
Function
Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase. .
Molecular Weight
3816030 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Titin
Subcellular Location
Cytoplasm . Nucleus .
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