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Anti-AID AICDA Antibody

Boster Bio Anti-AID AICDA Antibody catalog # A00267-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Single-stranded DNA cytosine deaminase;3.5.4.38; Activation-induced cytidine deaminase; Cytidine aminohydrolase; AICDA; AID

Gene Name

AICDA

UniProt

Q9GZX7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human AICDA. AA range:81-130

Tissue Specificity

Strongly expressed in lymph nodes and tonsils. .

Applications

WB, IHC

Purification

Immunogen affinity purified

Form

Liquid

Function

Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. .

Molecular Weight

23954 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Single-stranded DNA cytosine deaminase

Subcellular Location

Nucleus. Cytoplasm. Predominantly cytoplasmic but shuttles between the nucleus and the cytoplasm.

Curated Selection

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