Anti-IGF-1R (Ab-1161) Antibody
Boster Bio Anti-IGF-1R (Ab-1161) Antibody (Catalog # A00070-1) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
<br><br>Li S, et al. (1994) J Biol Chem; 269(51).
<br>Hernandez-Sanchez C, et al. (1995) J Biol Chem.
Gene Name
IGF1R
UniProt
P08069
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R .
Clonality
Polyclonal
Applications
WB, IHC, IF
Field of Research
Cancer, Developmental Biology, Growth Factors, Growth Factors/Hormones, Signal Transduction
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/ml
Form
Liquid
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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