Bremazocine
Bremazocine is a potent opioid kappa receptor agonist with analgesic activity. Bremazocine induces peripheral analgesia by releasing endogenous norepinephrine. The analgesic effect of bremazocine is associated with interaction with adenosine receptors. Bremazocine produces a dose-dependent peripheral analgesia after topical application. The effect of bremazocine is affected by nonselective α (2) adrenaline receptor antagonists, suggesting that it acts through a norepinephrine pathway[1].
Product Specifications
CAS Number
[75684-07-0]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bremazocine.html
Smiles
CC[C@]1(CCN2CC3(CC3)O)C4=CC(O)=CC=C4C[C@]2([H])C(C)1C
Molecular Formula
C20H29NO2
Molecular Weight
315.45
References & Citations
[1]Mu, delta, and kappa opioid receptor agonists induce peripheral antinociception by activation of endogenous noradrenergic system
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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