Cinoxate-d3
Product Specifications
UNSPSC Description
Cinoxate-d3 is deuterium labeled Cinoxate. Cinoxate is a hypertrophic peroxisome proliferator activating receptor γ (PPARγ) agonist with Ki value of 18.0 μM. Cinoxate can be used to study obesity[1][2].
Target Antigen
Isotope-Labeled Compounds; PPAR
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
O=C(OCCOCC)/C=C/C1=CC=C(OC([2H])([2H])[2H])C=C1
Molecular Weight
253.31
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]An S, et al. Cheminformatic Read-Across Approach Revealed Ultraviolet Filter Cinoxate as an Obesogenic Peroxisome Proliferator-Activated Receptor γ Agonist. Chem Res Toxicol. 2024 Aug 2.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
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