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Benproperine (phosphate)

Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis[1].

Product Specifications

CAS Number

19428-14-9

Product Name Alternative

1-O-hexyl-2,3,5-trimethylhydroquinone; HX-1171; BTT-105,YL0919

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Arp2/3 Complex

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/benproperine-phosphate.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

CC(N1CCCCC1)COC2=CC=CC=C2CC3=CC=CC=C3.O=P(O)(O)O

Molecular Formula

C21H30NO5P

Molecular Weight

407.44

Precautions

H302, H315, H319, H335

References & Citations

[1]Yae Jin Yoon, et al. Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis. Biochem Pharmacol. 2019 May;163:46-59.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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