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Probenecid (Standard)

Probenecid (Standard) is the analytical standard of Probenecid. This product is intended for research and analytical applications. Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels.

Product Specifications

CAS Number

[57-66-9]

UNSPSC

12352005

Hazard Statement

H302

Target

Bacterial; HIV; Reference Standards; TRP Channel

Type

Reference Standards

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/probenecid-standard.html

Purity

99.00

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)C1=CC=C(S(=O)(N(CCC)CCC)=O)C=C1

Molecular Formula

C13H19NO4S

Molecular Weight

285.36

Precautions

H302

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Citation 01

J Vet Intern Med. 2025 Sep-Oct;39 (5) :e70221.|ACS Environ Au. 2025 Aug 8.|Acta Pharmacol Sin. 2025 Sep 15.|Adv Sci (Weinh) . 2025 May 8:e2503579.|Adv Sci (Weinh) . 2025 Oct 6:e10270.|Anal Chem. 2025 Jun 3;97 (21) :11099-11109.|Biochem Biophys Res Commun. 2024 May 15:721:150128.|Biopharm Drug Dispos. 2022 Dec;43 (6) :265-271.|Cell Calcium. 2024 Apr 8, 102883.|Cell Mol Immunol. 2020 Mar;17 (3) :261-271.|Cell Rep. 2025 Mar 25;44 (4) :115466.|Cell Res. 2022 Jul;32 (7) :638-658.|Chem Biol Interact. 2024 Oct 29:111293.|Drug Deliv. 2025 Dec;32 (1) :2490269.|Exp Neurol. 2025 Jan:383:115040.|Food Res Int. 2025 Feb:201:115590. |Front Pharmacol. 2022 Feb 23:13:816133.|Front Pharmacol. 2022 Feb 23;13:816133.|Immunity. 2022 Apr 12;55 (4) :686-700.e7.|Int J Biol Sci. 2022 Apr 11;18 (7) :2914-2931.|Int J Mol Sci. 2019 Mar 5;20 (5) . pii: E1125. |J Agric Food Chem. 2016 Oct 26;64 (42) :7899-7910. |J Dig Dis. 2025 Jan-Feb;26 (1-2) :62-73.|J Endocrinol Invest. 2025 Feb;48 (2) :317-332.|J Transl Med. 2025 Jul 11;23 (1) :781.|Lasers Surg Med. 2017 Sep;49 (7) :719-726.|Mol Pharmacol. 2025 Oct 27.|Neuroscience. 2022 Jul 1:494:51-68.|Regul Toxicol Pharmacol. 2019 Nov:108:104449.|Res Sq. 2024 Nov 17.|Research Square Preprint. 2021 Aug.|Research Square Print. August 31st, 2022.|Toxicol Appl Pharmacol. 2024 Nov:492:117112.|Toxicol In Vitro. 2020 Dec;69:104971.|Transl Res. 2024 May 9:271:26-39.|World J Tradit Chin Med. 2025 August 01.

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