Complement factor D-IN-2
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases[1].
Product Specifications
CAS Number
[1903742-34-6]
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/complement-factor-d-in-2.html
Purity
99.33
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)[C@]5([H])C[C@]5([H])C1)NC6=NC(Br)=CC=C6
Molecular Formula
C27H24BrN7O3
Molecular Weight
574.43
References & Citations
[1]GADHACHANDA VR, et, al. Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders. WO2015130838A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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