LG 6-101
LG 6-101 is an orally active antiarrhythmic agent. LG 6-101 shows strong antiarrhythmic effects in a coronary-artery-ligation model of rats, better than Propafenone. LG 6-101 also delays the occurence of ventricular premature beat (VPB) 's and has protective effects against cardiac arrest caused by aconitine[1][2].
Product Specifications
CAS Number
132798-26-6
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lg-6-101.html
Smiles
O=C(CCC1=CC=CC=C1)C2=C(OCC(CNCC(C)C)OC)C(C)=CS2.Cl
Molecular Formula
C22H32ClNO3S
Molecular Weight
426.01
References & Citations
[1]Wascher TC, et al. LG 6-101 and LG 6-102, two new propafenone-related antiarrhythmic agents with good oral activity in rats. Naunyn Schmiedebergs Arch Pharmacol. 1992 Apr;345 (4) :473-7. |[2]Wascher TC, et al. Antiarrhythmic effects of two new propafenone related drugs. A study on four animal models of arrhythmia. Arzneimittelforschung. 1991 Feb;41 (2) :119-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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