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PROTAC Her3 Degrader-8

Product Specifications

UNSPSC Description

PROTAC Her3 Degrader-8 (Compound PP2) is a PROTAC that can degrade Her3 protein in vitro and cell experiments, and can be used to study diseases regulated by HER family proteins[1].

Target Antigen

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-her3-degrader-8.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=C2C(C(C=C3)=CC(NC(C=C)=O)=C3OC4=CC=CC=C4)=NN(C(CC5)CCN5CC(N[C@H](C(C)(C)C)C(N(C[C@H]6O)[C@H](C6)C(NCC7=CC=C(C(SC=N8)=C8C)C=C7)=O)=O)=O)C2=NC=N1

Molecular Weight

926.10

References & Citations

[1]Bifunctional molescules for her3 degradation and methods of use.WO2017117473.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-153796/PROTAC-Her3-Degrader-8-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-153796/PROTAC-Her3-Degrader-8-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2103331-95-7

Available Sizes

Curated Selection

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