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2-Phenylpropionic acid

2-Phenylpropionic acid is an intermediate in the metabolism of alpha-Methylstyrene. 2-Phenylpropionic acid covalently binds to rat liver protein. 2-Phenylpropionic acid can be used in the research of nonsteroidal anti-inflammatory agents[1][2][3].

Product Specifications

CAS Number

492-37-5

UNSPSC

12352005

Hazard Statement

H314

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-Phenylpropionic_acid.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : ≥ 100 mg/mL|H2O : 4.35 mg/mL (ultrasonic)

Smiles

C1=C(C(C(O)=O)C)C=CC=C1

Molecular Formula

C9H10O2

Molecular Weight

150.18

Precautions

H314

References & Citations

[1]De Costa KS, et al. Metabolism and disposition of alpha-methylstyrene in rats. Drug Metab Dispos. 2001 Feb;29 (2) :166-71.|[2]Li C, et al. Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes. Chem Res Toxicol. 2002 Nov;15 (11) :1480-7. |[3]Li C, et al. In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat. J Pharmacol Exp Ther. 2003 Apr;305 (1) :250-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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