2-Phenylpropionic acid
2-Phenylpropionic acid is an intermediate in the metabolism of alpha-Methylstyrene. 2-Phenylpropionic acid covalently binds to rat liver protein. 2-Phenylpropionic acid can be used in the research of nonsteroidal anti-inflammatory agents[1][2][3].
Product Specifications
CAS Number
492-37-5
UNSPSC
12352005
Hazard Statement
H314
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-Phenylpropionic_acid.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : ≥ 100 mg/mL|H2O : 4.35 mg/mL (ultrasonic)
Smiles
C1=C(C(C(O)=O)C)C=CC=C1
Molecular Formula
C9H10O2
Molecular Weight
150.18
Precautions
H314
References & Citations
[1]De Costa KS, et al. Metabolism and disposition of alpha-methylstyrene in rats. Drug Metab Dispos. 2001 Feb;29 (2) :166-71.|[2]Li C, et al. Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes. Chem Res Toxicol. 2002 Nov;15 (11) :1480-7. |[3]Li C, et al. In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat. J Pharmacol Exp Ther. 2003 Apr;305 (1) :250-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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