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NA/Neuraminidase, H3N2 (ACN50232, HEK293)

Selected Variant

HY-P73771

Size: 1 Each

NA/Neuraminidase Protein is a receptor-destroying enzyme that cleaves terminal sialic acids from cellular receptors, potentially facilitating viral invasion of the upper airways by targeting sialic acid moieties on airway epithelial cell mucin. NA plays a pivotal role in viral propagation by catalyzing the removal of terminal sialic acid residues from both viral and cellular glycoconjugates. Moreover, the sialidase activity in late endosome/lysosome traffic appears to enhance virus replication. NA/Neuraminidase Protein, H3N2 (ACN50232, HEK293) is the recombinant Virus-derived NA/Neuraminidase protein, expressed by HEK293 , with tag free. It originates from cell lysates collected after expressing a DNA sequence encoding the Influenza A virus neuraminidase.

Product Specifications

Product Name Alternative

NA/Neuraminidase Protein, H3N2 (ACN50232, HEK293), Virus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/na-neuraminidase-protein-h3n2-acn50232-hek293.html

Molecular Formula

/ (Gene_ID) ACN50232 (H36-P459) (Accession)

References & Citations

[1]von Itzstein M. The war against influenza: discovery and development of sialidase inhibitors. Nat Rev Drug Discov. 2007 Dec;6 (12) :967-74.|[2]Palese P, et al. Characterization of temperature sensitive influenza virus mutants defective in neuraminidase. Virology. 1974 Oct;61 (2) :397-410.|[3]Liu C, et al. Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding. J Virol. 1995 Feb;69 (2) :1099-106.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Price

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