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Lupeol acetate

Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory, antibacterial, anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility[1][2][3][4].

Product Specifications

CAS Number

[1617-68-1]

UNSPSC

12352211

Target

Bacterial; COX; Fungal; Interleukin Related; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lupeol-acetate.html

Purity

98.0

Solubility

Ethanol : ≥ 2 mg/mL

Smiles

C[C@@]([C@@]1(CC[C@@]2([H])C3(C)C)C)(CC4)[C@@](CC[C@]1([H])[C@]2(CC[C@@H]3OC(C)=O)C)([H])[C@]([C@@H]5C(C)=C)([H])[C@@]4(CC5)C

Molecular Formula

C32H52O2

Molecular Weight

468.75

References & Citations

[1]Wang WH, et al. Lupeol acetate ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment. Biomed Pharmacother. 2016;79:231-240.|[2]Javed S, et al. Lupeol acetate as a potent antifungal compound against opportunistic human and phytopathogenic mold Macrophomina phaseolina. Sci Rep. 2021 Apr 19;11 (1) :8417. |[3]Pardo-Rodriguez D, et al. Lupeol Acetate and α-Amyrin Terpenes Activity against Trypanosoma cruzi: Insights into Toxicity and Potential Mechanisms of Action. Trop Med Infect Dis. 2023 May 3;8 (5) :263.|[4]Gupta RS, et al. Induction of antifertility with lupeol acetate in male albino rats. Pharmacology. 2005 Oct;75 (2) :57-62.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

COX-2

Available Sizes

Curated Selection

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