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Omeprazole-d3

Omeprazole-d3 (H 16868-d3) is deuterium labeled Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].

Product Specifications

CAS Number

922731-01-9

Product Name Alternative

H 16868-d3

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Autophagy; Bacterial; Proton Pump

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Autophagy; Membrane Transporter/Ion Channel

Field of Research

Cancer; Infection; Metabolic Disease

Purity

98.99

Solubility

DMSO : 125mg/mL (ultrasonic)

Smiles

CC(C(OC)=C(C)C=N1)=C1CS(C2=NC3=CC=C(OC([2H])([2H])[2H])C=C3N2)=O

Molecular Formula

C17H16D3N3O3S

Molecular Weight

348.43

Precautions

H315, H319, H335

References & Citations

[1]Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32 (8) :821-7.|[2]Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37 (1) :145-50.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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