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Erythromycin ethylsuccinate-13C, d3

Erythromycin ethylsuccinate-13C, d3 is the 13C- and deuterium labeled Erythromycin Ethylsuccinate. Erythromycin Ethylsuccinate is an antibiotic useful for the treatment of a number of bacterial infections, has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin Ethylsuccinate has antiviral activity against HIV-1.

Product Specifications

Product Name Alternative

Erythromycin ethyl succinate-13C, d3; EES-13C, d3

UNSPSC

12352005

Target

Antibiotic; Autophagy; Bacterial; HIV; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Autophagy; Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

O=C(O[C@H]1[C@H](O[C@@H]([C@](C)(O)C[C@H]2C)[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C2=O)=O)O[C@H](C)C[C@@H]1N(C)[13C]([2H])([2H])[2H])CCC(OCC)=O

Molecular Formula

C42 13CH72D3NO16

Molecular Weight

866.06

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[2]Feng YC, et al. Construction of universal quantitative models for determination of roxithromycin and erythromycin ethylsuccinate in tablets from different manufacturers using near infrared reflectance spectroscopy. J Pharm Biomed Anal. 2006 May 3;41 (2) :373-84.|[3]Gustafsson A, et al. The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden. Equine Vet J. 1997 Jul;29 (4) :314-8.|[4]Komuro I, et al. Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta. Proc Natl Acad Sci U S A. 2008 Aug 26;105 (34) :12509-14.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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