AGRP rabbit pAb
Disease: Defects in AGRP may be a cause of autosomal dominant obesity [MIM: 601665]. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. function: Plays a role in weight homeostasis. May play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding. similarity: Contains 1 agouti domain. tissue specificity: Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
Product Specifications
Background
Synonyms
Agouti-related protein
Gene ID
181
UniProt
O00253
Cellular Locus
Secreted. Golgi apparatus lumen.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human AGRP AA range: 21-70
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20302-1.pdf
Subcellular Location
Secreted . Golgi apparatus lumen .
Other Product Names
Agouti-related protein
Gene ID (Human)
181
SwissProt (Human)
O00253
Available Sizes
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