AGRP rabbit pAb
Disease: Defects in AGRP may be a cause of autosomal dominant obesity [MIM: 601665]. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. function: Plays a role in weight homeostasis. May play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding. similarity: Contains 1 agouti domain. tissue specificity: Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
Product Specifications
Background
UniProt
O00253
Swiss Prot
O00253
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human AGRP AA range: 21-70
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted . Golgi apparatus lumen .
Other Product Names
Agouti-related protein
Gene ID (Human)
181
Available Sizes
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