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Ixabepilone (Standard)

Ixabepilone (Standard) is the analytical standard of Ixabepilone. This product is intended for research and analytical applications. Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.

Product Specifications

CAS Number

219989-84-1

Product Name Alternative

BMS-247550 (Standard) ; Aza-epothilone B (Standard)

UNSPSC

12352005

Target

Apoptosis; Bacterial; Microtubule/Tubulin; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ixabepilone-standard.html

Smiles

O=C([C@@H]([C@H]([C@H](CCC[C@]1(O[C@]1(C[C@H](N2)/C(C)=C/C3=CSC(C)=N3)[H])C)C)O)C)C(C)([C@H](CC2=O)O)C

Molecular Formula

C27H42N2O5S

Molecular Weight

506.70

References & Citations

[1]John T. Hunt Discovery of Ixabepilone. Mol Cancer Ther February 2009 8; 275

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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