Prion Protein, Recombinant

<strong>Prion Protein, Recombinant</strong>_x000D_ <strong>Catalog number:</strong> B2019332_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 27 kD_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Prion Protein, Recombinant_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ma J, Zhang J, Yan R. Recombinant Mammalian Prions: The "Correctly" Misfolded Prion Protein Conformers Viruses. 2022 Aug 31;14(9):1940._x000D_ 2: Yuan J, Zhan YA, Abskharon R, Xiao X, Martinez MC, Zhou X, Kneale G, Mikol J, Lehmann S, Surewicz WK, Castilla J, Steyaert J, Zhang S, Kong Q, Petersen RB, Wohlkonig A, Zou WQ. Recombinant human prion protein inhibits prion propagation in vitro Sci Rep. 2013 Oct 9;3:2911._x000D_ 3: Imamura M, Tabeta N, Iwamaru Y, Takatsuki H, Mori T, Atarashi R. Spontaneous generation of distinct prion variants with recombinant prion protein from a baculovirus-insect cell expression system Biochem Biophys Res Commun. 2022 Jul 12;613:67-72._x000D_ 4: Aguilar-Calvo P, Malik A, Sandoval DR, Barback C, Orrù CD, Standke HG, Thomas OR, Dwyer CA, Pizzo DP, Bapat J, Soldau K, Ogawa R, Riley MB, Nilsson KPR, Kraus A, Caughey B, Iliff JJ, Vera DR, Esko JD, Sigurdson CJ. Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection PLoS Pathog. 2023 Sep 25;19(9):e1011487._x000D_ 5: Requena JR, Wille H. The Structure of the Infectious Prion Protein and Its Propagation Prog Mol Biol Transl Sci. 2017;150:341-359._x000D_ 6: Imamura M, Mori T, Takatsuki H, Iwamaru Y, Atarashi R. [Elucidation of the Molecular Basis of Abnormal Prion Protein (PrP) Formation in a Cell-Free System Using Baculovirus and Insect Cell-derived Recombinant PrP] Yakugaku Zasshi. 2019;139(7):989-992._x000D_ 7: Wang F, Wang X, Orrú CD, Groveman BR, Surewicz K, Abskharon R, Imamura M, Yokoyama T, Kim YS, Vander Stel KJ, Sinniah K, Priola SA, Surewicz WK, Caughey B, Ma J. Self-propagating, protease-resistant, recombinant prion_protein conformers with or without in vivo pathogenicity PLoS Pathog. 2017 Jul 12;13(7):e1006491._x000D_ 8: Kopycka K, Maddison BC, Gough KC. Recombinant ovine prion_protein can be mutated at position 136 to improve its efficacy as an inhibitor of prion propagation Sci Rep. 2023 Mar 1;13(1):3452._x000D_ 9: Schmidt C, Fizet J, Properzi F, Batchelor M, Sandberg MK, Edgeworth JA, Afran L, Ho S, Badhan A, Klier S, Linehan JM, Brandner S, Hosszu LL, Tattum MH, Jat P, Clarke AR, Klöhn PC, Wadsworth JD, Jackson GS, Collinge J. A systematic investigation of production of synthetic prions from recombinant prion_protein Open Biol. 2015 Dec;5(12):150165._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31455808">10: Kovachev PS, Gomes MPB, Cordeiro Y, Ferreira NC, Valadão LPF, Ascari LM, Rangel LP, Silva JL, Sanyal S. RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction Sci Rep. 2019 Aug 27;9(1):12406. </a>_x000D_ _x000D_ <strong>Products Related to Prion Protein, Recombinant can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>