Human Methylmalonyl CoA Epimerase

<strong>Human Methylmalonyl CoA Epimerase</strong>_x000D_ <strong>Catalog number:</strong> B2012333_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 17.3kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> fluorescent dye commonly used as a tracer agent_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Methylmalonyl CoA Epimerase, Glyoxalase Domain Containing 2, DL-methylmalonyl-CoA Racemase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Manoli I, Sloan JL, Venditti CP. Isolated Methylmalonic Acidemia 2005 Aug 16 [updated 2022 Sep 8]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2022._x000D_ 2: Abily-Donval L, Torre S, Samson A, Sudrié-Arnaud B, Acquaviva C, Guerrot AM, Benoist JF, Marret S, Bekri S, Tebani A. Methylmalonyl-CoA Epimerase Deficiency Mimicking Propionic Aciduria Int J Mol Sci. 2017 Nov 1;18(11):2294._x000D_ 3: Heuberger K, Bailey HJ, Burda P, Chaikuad A, Krysztofinska E, Suormala T, Bürer C, Lutz S, Fowler B, Froese DS, Yue WW, Baumgartner MR. Genetic, structural, and functional analysis of pathogenic variations causing methylmalonyl-CoA epimerase deficiency Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1265-1272._x000D_ 4: Bobik TA, Rasche ME. HPLC assay for methylmalonyl-CoA epimerase Anal Bioanal Chem. 2003 Feb;375(3):344-9._x000D_ 5: Bobik TA, Rasche ME. Identification of the human methylmalonyl-CoA racemase gene based on the analysis of prokaryotic gene arrangements. Implications for decoding the human genome J Biol Chem. 2001 Oct 5;276(40):37194-8._x000D_ 6: Chandler RJ, Aswani V, Tsai MS, Falk M, Wehrli N, Stabler S, Allen R, Sedensky M, Kazazian HH, Venditti CP. Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism Mol Genet Metab. 2006 Sep-Oct;89(1-2):64-73._x000D_ 7: Waters PJ, Thuriot F, Clarke JT, Gravel S, Watkins D, Rosenblatt DS, Lévesque S. Methylmalonyl-coA epimerase deficiency: A new case, with an acute metabolic presentation and an intronic splicing mutation in the MCEE gene Mol Genet Metab Rep. 2016 Sep 24;9:19-24._x000D_ 8: Kühnl J, Bobik T, Procter JB, Burmeister C, Höppner J, Wilde I, Lüersen K, Torda AE, Walter RD, Liebau E. Functional analysis of the methylmalonyl-CoA epimerase from Caenorhabditis elegans FEBS J. 2005 Mar;272(6):1465-77._x000D_ 9: Dobson CM, Gradinger A, Longo N, Wu X, Leclerc D, Lerner-Ellis J, Lemieux M, Belair C, Watkins D, Rosenblatt DS, Gravel RA. Homozygous nonsense mutation in the MCEE gene and siRNA suppression of methylmalonyl-CoA epimerase expression: a novel cause of mild methylmalonic aciduria Mol Genet Metab. 2006 Aug;88(4):327-33._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17823972">10: Gradinger AB, Bélair C, Worgan LC, Li CD, Lavallée J, Roquis D, Watkins D, Rosenblatt DS. Atypical methylmalonic aciduria: frequency of mutations in the methylmalonyl CoA epimerase gene (MCEE) Hum Mutat. 2007 Oct;28(10):1045. </a>_x000D_ _x000D_ <strong>Products Related to Human Methylmalonyl CoA Epimerase can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>