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SUN11602

SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity.

Product Specifications

CAS Number

704869-38-5

UNSPSC

12352005

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/SUN11602.html

Purity

98.00

Solubility

DMSO : ≥ 37 mg/mL

Smiles

O=C(N)C1=CC=C(CN2CCC(N(C(CNC3=C(C)C(C)=C(N)C(C)=C3C)=O)C)CC2)C=C1

Molecular Formula

C26H37N5O2

Molecular Weight

451.60

References & Citations

[1]Murayama N, et al. SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. ACS Chem Neurosci. 2013 Feb 20;4 (2) :266-76.|[2]Murayama N, et al. SUN11602-induced hyperexpression of calbindin D-28k is pivotal for the survival of hippocampal neurons under neurotoxic conditions. Brain Res. 2015 Jan 12;1594:71-81.|[3]Ogino R, et al. SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer's disease induced by amyloid β and excitatory amino acids. Brain Res. 2014 Oct 17;1585:159-66.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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