BB-Cl-Yne

BB-Cl-Yne is a protein arginine deiminase (PAD) inhibitor with Ki values of PAD1-4.are 6400, 3600, 10800, 4900 M-1min-1 respectively. BB-Cl-Yne can be used as a click probe to label PAD[1].

Product Specifications

CAS Number

[2219324-71-5]

UNSPSC

12352005

Target

Protein Arginine Deiminase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bb-cl-yne.html

Smiles

O=C(C1=CC=C(C2=CC=C(C#C)C=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N

Molecular Formula

C28H26ClN5O

Molecular Weight

483.99

References & Citations

[1]Nemmara VV, et al. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs) . ACS Chem Biol. 2018 Mar 16;13 (3) :712-722.