Guanoxyfen (nitrate)
Guanoxyfen (N- (3-Phenoxypropyl) guanidine) nitrate is a compound that exhibits potent inhibitory activity against the serine protease enzyme TMPRSS2, which plays a crucial role in the infectivity of coronaviruses. Guanoxyfen nitrate is also an effective inhibitor of vasoconstrictor responses to sympathetic nerve stimulation.
Product Specifications
CAS Number
860385-36-0
Product Name Alternative
N- (3-Phenoxypropyl) guanidine (nitrate) ; (3-Phenoxypropyl) guanidine (nitrate)
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/guanoxyfen-nitrate.html
Smiles
N=C(N)NCCCOC1=CC=CC=C1.[O-][N+](O)=O
Molecular Formula
C10H16N4O4
Molecular Weight
256.26
References & Citations
[1]Docking-generated multiple ligand poses for bootstrapping bioactivity classifying Machine Learning: Repurposing covalent inhibitors for COVID-19-related TMPRSS2 as case study
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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