Thiacloprid

Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].

Product Specifications

CAS Number

[111988-49-9]

UNSPSC

12352005

Hazard Statement

H301

Target

DNA Stain; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/thiacloprid.html

Purity

99.66

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

N#C/N=C1N(CCS/1)CC(C=C2)=CN=C2Cl

Molecular Formula

C10H9ClN4S

Molecular Weight

252.72

Precautions

H301

References & Citations

[1]Schuld, M., et al. Effects of Thiacloprid, a New Chloronicotinyl Insecticide, On the Egg Parasitoid Trichogramma cacaoeciae. Ecotoxicology 9, 197–205 (2000) .|[2]Verebová V, Želonková K, Holečková B, Staničová J. The effect of neonicotinoid insecticide thiacloprid on the structure and stability of DNA. Physiol Res. 2019;68 (Suppl 4) :S459-S466.