6-Chloro-2-iodo-9- (2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl) purine
Selected Variant
HY-W010757-01
Size: 10 mg
6-Chloro-2-iodo-9- (2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl) purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
5987-76-8
UNSPSC
12352005
Hazard Statement
H302
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-chloro-2-iodo-9-2-3-5-tri-o-acetyl-β-d-ribofuranosyl-purine.html
Solubility
10 mM in DMSO
Smiles
CC(OC[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](N2C(N=C(I)N=C3Cl)=C3N=C2)O1)=O
Molecular Formula
C16H16ClIN4O7
Molecular Weight
538.68
Precautions
P264-P270-P330-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Price
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