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mmu-miR-224-5p antagomir

Product Specifications

UNSPSC Description

mmu-miR-224-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

Target Antigen

MicroRNA

Type

Oligonucleotides

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmu-mir-224-5p-antagomir.html

Purity

98.93

Solubility

10 mM in H2O

Molecular Weight

7053.619

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-RI02850A/mmu-miR-224-5p-antagomir-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-RI02850A/mmu-miR-224-5p-antagomir-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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