ARN14686

ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM) . ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe[1].

Product Specifications

CAS Number

[1628345-10-7]

UNSPSC

12352005

Target

Fluorescent Dye

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/arn14686.html

Smiles

O=C(OCCCCCCCCCC#C)N[C@H]1CNC1=O

Molecular Formula

C15H24N2O3

Molecular Weight

280.36

References & Citations

[1]Romeo E, et al. Activity-Based Probe for N-Acylethanolamine Acid Amidase. ACS Chem Biol. 2015 Sep 18;10 (9) :2057-2064.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

51270151 3x 1.0 µg DNA

ZMAT5 CRISPR All-in-one AAV vector set (with saCas9)(Human)

Ask

View Details

NBP2-34655H 0.1 mL

Mouse Monoclonal Cytokeratin 8/18 Antibody (K8.8 + DC10) [HRP]

Ask

View Details

MBS9312315 Inquire

Simian apoprotein A1, apo-A1 ELISA Kit

Ask

View Details

MBS050057-01 48 Well

Bovine Proteasome Subunit Alpha Type 1 ELISA Kit

Ask

View Details

MBS050057-02 96 Well

Bovine Proteasome Subunit Alpha Type 1 ELISA Kit

Ask

View Details

MBS050057-03 5x 96 Well

Bovine Proteasome Subunit Alpha Type 1 ELISA Kit

Ask

View Details