ARN14686
ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM) . ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe[1].
Product Specifications
CAS Number
[1628345-10-7]
UNSPSC
12352005
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arn14686.html
Smiles
O=C(OCCCCCCCCCC#C)N[C@H]1CNC1=O
Molecular Formula
C15H24N2O3
Molecular Weight
280.36
References & Citations
[1]Romeo E, et al. Activity-Based Probe for N-Acylethanolamine Acid Amidase. ACS Chem Biol. 2015 Sep 18;10 (9) :2057-2064.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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