SLC40A1, Human (Sf9, His, MBP, FLAG)

SLC40A1 plays a pivotal role in systemic iron homeostasis by transporting Fe(2+) from cells to the bloodstream. Essential for maintaining iron balance, it enables dietary iron uptake, recycling by macrophages and erythrocytes, and controlled release from hepatocytes. In iron surplus, elevated HAMP/hepcidin levels prompt SLC40A1 degradation, limiting iron efflux into the plasma. SLC40A1 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC40A1 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC40A1 Protein, Human (Sf9, His, MBP, FLAG) is 570 a.a., .