Glucoraphenin (potassium)

Glucoraphenin potassium induces xenobiotic metabolizing enzymes (XMEs) . Glucoraphenin potassium, the predominant and orally active glucosinolate in radish sprouts, is hydrolyzed by myrosinase to sulforaphene that is implicated to exert anticancerogenic effects[1][2].

Product Specifications

CAS Number

[108844-81-1]

UNSPSC

12352005

Hazard Statement

H317

Target

Drug Intermediate

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glucoraphenin-potassium.html

Purity

99.05

Solubility

10 mM in DMSO

Smiles

CS(/C=C/CC/C(S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)=N/OS(=O)(O[K])=O)=O

Molecular Formula

C12H20KNO10S3

Molecular Weight

473.58

Precautions

H317

References & Citations

[1]Ruimin Li, et al. Glucoraphenin, sulforaphene, and antiproliferative capacity of radish sprouts in germinating and thermal processes. European Food Research and Technology volume 243, pages547–554 (2017) .|[2]Jessica Barillari, et al. Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats. J Agric Food Chem. 2007 Jul 11;55 (14) :5505-11.