TCO-PNB ester
TCO-PNB ester is an amine-reactive building block used for modification of amine-containing molecule. TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group[1].
Product Specifications
CAS Number
[1438415-89-4]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tco-pnb-ester.html
Purity
98.52
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=C([N+]([O-])=O)C=C1)O[C@H]2CC/C=C/CCC2
Molecular Formula
C15H17NO5
Molecular Weight
291.30
Precautions
H315, H319, H335
References & Citations
[1]Bidesi N, et al. Synthesis and radiolabeling of a polar [125 I]I-1,2,4,5-tetrazine. J Labelled Comp Radiopharm. 2023 Jan;66 (1) :22-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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